Tag: bioinformatics
-
**Modern Trends in Innovation and Sustainability Across Various Sectors**
**Introduction to an Article on Technological Innovations and Their Impact in Various Fields** The world today has become a rapidly changing place due to technological transformations and the digital revolution affecting all aspects of life. Technological advancement is no longer just a means to improve efficiency; it has transcended that to become the foundation for…
-
The Complex Relationship Between Chondrocyte Autophagy and Osteoarthritis
Osteoarthritis (OA) is considered one of the most common types of arthritis in the world, characterized by the gradual degeneration of cartilage, which is closely associated with the autophagic processes of chondrocytes. These cells, which are the only elements found in articular cartilage, play a vital role in maintaining cartilage equilibrium. Although autophagy is considered…
-
The Complex Relationship Between Autophagy of Chondrocytes and Osteoarthritis
Osteoarthritis (OA) is considered one of the most common types of arthritis in the world, characterized by the gradual deterioration of cartilage, which is closely related to the autophagic processes of chondrocytes. These cells, which are the only elements in articular cartilage, play a vital role in maintaining cartilage balance. Although autophagy is considered a…
-
CmdTAC System for Defense Against Viruses in Escherichia coli: A New Mechanism for mRNA Modification
The ADP-ribosyltransferases transfer enzymes are considered essential in biology, as they are characterized by their ability to transfer an ADP-ribose molecule from NAD+ to other biomolecules, contributing to the modification of amino acids in target proteins. The process of ADP-ribosylation is one of the most common post-translational modifications and plays a pivotal role in regulating…
-
CmdTAC System for Defense Against Viruses in Escherichia coli: A New Mechanism for mRNA Modification
The ADP-ribosyltransferases transfer enzymes are considered essential in biology, as they are characterized by their ability to transfer an ADP-ribose molecule from NAD+ to other biomolecules, contributing to the modification of amino acids in target proteins. The process of ADP-ribosylation is one of the most common post-translational modifications and plays a pivotal role in regulating…
-
CmdTAC System for Defense Against Viruses in Escherichia coli: A New Mechanism for mRNA Modification
The ADP-ribosyltransferases transfer enzymes are considered essential in biology, as they are characterized by their ability to transfer an ADP-ribose molecule from NAD+ to other biomolecules, contributing to the modification of amino acids in target proteins. The process of ADP-ribosylation is one of the most common post-translational modifications and plays a pivotal role in regulating…
-
CmdTAC System for Defense Against Viruses in Escherichia coli: A New Mechanism for mRNA Modification
The ADP-ribosyltransferases transfer enzymes are considered essential in biology, as they are characterized by their ability to transfer an ADP-ribose molecule from NAD+ to other biomolecules, contributing to the modification of amino acids in target proteins. The process of ADP-ribosylation is one of the most common post-translational modifications and plays a pivotal role in regulating…
-
CmdTAC System for Antiviral Defense in Escherichia coli: A Novel mRNA Editing Mechanism
ADP-ribosyltransferases are considered essential elements in biology, characterized by their ability to transfer an ADP-ribose molecule from NAD+ to other biomolecules, contributing to the modification of amino acids in target proteins. The process of ADP-ribosylation is one of the most common post-translational modifications and plays a pivotal role in regulating various proteins involved in cellular…
-
CmdTAC System for Antiviral Defense in Escherichia coli: A Novel mRNA Editing Mechanism
ADP-ribosyltransferases are considered essential elements in biology, characterized by their ability to transfer an ADP-ribose molecule from NAD+ to other biomolecules, contributing to the modification of amino acids in target proteins. The process of ADP-ribosylation is one of the most common post-translational modifications and plays a pivotal role in regulating various proteins involved in cellular…
-
The effect of Bacillus subtilis KC1 on improving the growth performance of chicks infected with Mycoplasma gallisepticum.
The bacterium “Bacillus subtilis” is considered one of the most prominent food additives used in the poultry industry to enhance bird health and performance. In this context, the current article addresses a new study aimed at understanding how “Bacillus subtilis KC1” can improve the growth of broiler chickens infected with “Mycoplasma gallisepticum” (MG), which is…
-
Developments in Comparative Genomics and Pan-genomics: Tools and New Perspectives on Gene and Genome Evolution
In light of the rapid advancements in the field of genomics and DNA sequencing technologies, the fields of comparative genomics and pangenomics have emerged as vital tools for understanding the genetic diversity and evolution of microorganisms. Over the past few decades, we have witnessed groundbreaking shifts, from the first generation of DNA sequencing techniques to…
-
Sustainability of Agriculture Through Enhancing Soil Microbiomes for Food Security
Soil health is considered one of the essential elements in responding to the increasing demand for food resulting from the growing global population. Microbes play a vital role in enhancing this health by managing nutrient cycles, breaking down pollutants, and maintaining soil structure. This article focuses on applicable microbial solutions in sustainable agriculture, highlighting the…
-
Biological Analysis of the Immune Microenvironment in Liver Cancer with Portal Vein Thrombosis and Its Impact on Clinical Outcomes
Liver diseases, particularly hepatocellular carcinoma (HCC), have seen a significant increase worldwide, with this type of cancer being the most common among primary liver cancers. Patients diagnosed with liver cancer who suffer from portal vein thrombosis (PVTT) face substantial challenges related to disease progression and elevated mortality rates. This study highlights the vital role of…
-
Analysis of Species Diversity in Zooplankton Using Environmental DNA Sequencing Techniques
In light of global environmental changes and the increasing interest in marine species diversity, studying species diversity from marine ecosystems has become vital. This article focuses on research conducted in the Ulleng Basin in South Korea, known for its rich diversity of zooplankton species. By integrating two innovative techniques, bulk DNA analysis and environmental DNA…
-
Mitochondrial Mechanisms in Sick Sinus Syndrome
The sick sinus syndrome (SSS) is a serious medical condition that can lead to sudden death. Despite the multiple research studies regarding this condition, its underlying mechanism is still not fully discovered. Previous studies state that the increase in fibrosis in the sinus node and surrounding tissues, along with disorders of the natural pacemaker system,…
-
Improving Atomoxetine Dosage for the Treatment of Attention Deficit Hyperactivity Disorder in Children: The Need for Personalized Pharmacovigilance
In recent years, Attention Deficit Hyperactivity Disorder (ADHD) has become one of the most common neurodevelopmental disorders among children, highlighting the urgent need for effective and tailored therapeutic strategies. In this context, the substance “Atomoxetine” emerges as a non-stimulant medication, recognized in various clinical guidelines as an important alternative to stimulant treatments. Although the effectiveness…
-
Identification of Parasitic Species of the Genus Eimeria in Camels in Riyadh, Saudi Arabia: Morphological and Genetic Study
Coccidiosis is considered one of the serious parasitic diseases affecting camels, caused by protozoan parasites of the genus “Eimeria,” leading to significantly reduced milk and meat production. In the Kingdom of Saudi Arabia, the scientific literature lacks studies focusing on the virological examinations of dromedary camels (Camelus dromedarius). Therefore, we conducted a comprehensive study to…
-
Study of the Relationship between Genes Associated with Sulphur-Dependent Cell Death and Outcomes in Glioma Patients
Glioblastoma (GBM) is considered one of the most aggressive types of cancer in the central nervous system, posing a significant challenge in the field of standard treatment due to its aggressiveness and the limited survival time of patients affected by it. In recent years, new research has emerged to uncover the molecular mechanisms responsible for…
-
Defining the Role of Chromatin Regulators in Lung Adenocarcinoma and Their Impact on Survival Outcomes and Immune Response
Introduction: Lung cancer is a major source of cancer-related deaths, with incidence rates continuing to rise worldwide. Chromatin remodeling, as a vital biological process in regulating gene expression, is a key factor in the development and progression of malignant tumors. However, the role of chromatin regulators in lung adenocarcinoma (LUAD) remains insufficiently explored. In this…
-
The Evolution of Genetic Clones and Interaction with the Tumor Microenvironment Across Different Types of Cancer
Introduction: Resistance to therapies remains one of the most prominent challenges facing cancer research, as subpopulations develop to sustain the survival of cancer cells in a complex environment. In this context, this article addresses the role of the tumor microenvironment in enhancing this resistance through various mechanisms. It will review how modern technologies such as…
-
**”Innovations in Life Sciences: Steps Towards a Healthy and Sustainable Future”**
In a rapidly evolving world, the biosciences emerge as a pivotal element contributing to changing the course of healthcare and addressing major health challenges. These sciences are considered a incubator for innovations and modern technologies aimed at improving human health and the quality of life, ranging from advanced treatments for genetic diseases to precise prevention…
-
Development of Monoclonal Antibodies Derived from Plants to Combat the Monkeypox Virus
The monkeypox virus (MPXV) is a double-stranded DNA virus, which experienced a global outbreak in 2022 with increased transmission among humans, necessitating urgent public health intervention. The health challenges associated with MPXV include the development of effective treatments targeting its infectious forms, including mature virions (MV) and enveloped extracellular virions (EV). As part of broader…
-
“Biotechnology: Innovations and Prospects in Enhancing Public Health”
## Exploring Innovations in Biotechnology: Towards a Healthy and Prosperous World ### 1. Introduction: The Importance of Biotechnology in Improving Human Health In light of the increasing health challenges facing the world, biotechnology emerges as one of the most prominent innovation tools that contribute to reducing these challenges and improving individuals’ quality of life. By…
-
The Inhibitory Effect of RIG-I Receptor Pathway on Survival Rate in a Klebsiella Pneumonia-Induced Lung Inflammation Model
Pneumonia is considered a common clinical condition that poses a serious threat to public health, with high mortality rates recorded among patients in intensive care units. Traditional treatment for pneumonia relies on antibiotics and organ support, but the lack of supportive treatments targeting the underlying mechanisms of the disease represents a significant challenge. In this…